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Actonel
Pronounced: AK-ton-ell
Generic name: Risedronate
Although our bones seem solid and stable, they actually undergo constant renewal. Specialized cells called osteoclasts draw used calcium out of the bones while other cells called osteoblasts replace it. Especially after menopause, this process can get out of balance. Calcium starts to leach out of the bones faster than it can be replaced, leading to the brittle-bone disease called osteoporosis.
Actonel combats this problem by reducing the activity of the osteoclasts and slowing the loss of calcium from the bones. It is prescribed for postmenopausal women, both to prevent osteoporosis and to strengthen the bones once the disease has begun. It is also used in the treatment of Paget's disease, a condition in which patches of bone become softened and enlarged.
Risedronate should be taken with a full glass (6-8 ounces) of water on an empty stomach and at least 30 minutes before any food. It is also important that you remain upright (do not lie down) for 30 minutes after taking this medication.
Both Actonel and similar drugs called Allendronate (Fosamax), Etidronate (Didronel in the U.S. and Didrocal in Canada) are members of the family of drugs called bisphosphonates.
ADULTS
Osteoporosis
For the prevention and treatment of osteoporosis, the recommended dose is one 5-milligram tablet once daily.
Paget's Disease
The recommended dose for Paget's disease is 30 milligrams once a day for two months. A second 2-month course of therapy may be required in certain individuals. |
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