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Lotensin
Pronounced: Lo-TEN-sin
Generic name: Benazepril hydrochloride
Lotensin is used in the treatment of high blood pressure. It is effective when used alone or in combination with thiazide diuretics. Lotensin is in a family of drugs called ACE (angiotensin-converting enzyme) inhibitors. It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Lotensin also enhances blood flow throughout your blood vessels.
ADULTS
For people not taking a diuretic drug, the usual starting dose is 10 milligrams, once a day. Regular total dosages range from 20 to 40 milligrams per day either taken in a single dose or divided into 2 equal doses. The maximum dose is 80 milligrams per day. Your doctor will closely monitor the effect of this drug and adjust it according to your individual needs.
For people already taking a diuretic, the diuretic should be stopped, if possible, 2 to 3 days before taking Lotensin. This reduces the possibility of fainting or light-headedness. If blood pressure cannot be controlled by Lotensin alone, then diuretic use should begin again. If the diuretic cannot be discontinued, the starting dosage of Lotensin should be 5 milligrams.
For people with reduced kidney function, the dosages should be individualized according to the amount of reduced function. The usual starting dose in these instances is 5 milligrams per day, adjusted upwards to a maximum of 40 milligrams per day.
CHILDREN
The safety and effectiveness of Lotensin have not been established in children. |
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