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Sinemet-CR
Pronounced: SIN-uh-met see-are
Generic ingredients: Carbidopa, Levodopa
Sinemet CR is a controlled-release tablet that may be given to help relieve the muscle stiffness, tremor, and weakness caused by Parkinson's disease. It may also be given to relieve Parkinson-like symptoms caused by encephalitis (brain fever), carbon monoxide poisoning, or manganese poisoning.
Sinemet CR contains two drugs, carbidopa and levodopa. The drug that actually produces the anti-Parkinson's effect is levodopa. Carbidopa helps to get levodopa into the brain, thus allowing levodopa to work more efficiently.
Parkinson's drugs such as Sinemet CR relieve the symptoms of the disease, but are not a permanent cure.
Your doctor will tailor your individual dosage carefully, depending on your response to previous therapy and symptoms.
ADULTS
For patients with mild to moderate symptoms, the initial recommended dose is 1 tablet of Sinemet CR taken 2 times a day.
Starting doses should be spaced out every 4 to 8 hours and then adjusted to each patient's individual response.
The usual long-term dose is 2 to 8 tablets per day, taken in divided doses every 4 to 8 hours during the waking day.
Higher doses (12 or more tablets per day) and shorter intervals (less than 4 hours) have been used, but are not usually recommended.
When doses of Sinemet CR are given at intervals of less than 4 hours, and/or if the divided doses are not equal, it is recommended that the smaller doses be given at the end of the day.
An interval of at least 3 days between dosage adjustments is recommended.
Dosage adjustment of Sinemet CR may be necessary if your doctor prescribes additional medications.
CHILDREN
Use of Sinemet CR in children under 18 is not recommended. |
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