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Zestoretic
Pronounced: zest-or-ET-ik
Generic ingredients: Lisinopril, Hydrochlorothiazide
Other brand name: Prinzide
Zestoretic is used in the treatment of high blood pressure. It combines an ACE inhibitor drug with a diuretic. Lisinopril, the ACE inhibitor, works by limiting production of a substance that promotes salt and water retention in your body. Hydrochlorothiazide, a diuretic, prompts your body to produce and eliminate more urine, which helps in lowering blood pressure. Combination products such as Zestoretic are usually not prescribed until therapy is already under way.
ADULTS
Zestoretic is designed to replace higher doses of either component. Dosages of the lisinopril component range from 10 to 80 milligrams a day; dosages of hydrochlorothiazide typically fall between 6.25 and 50 milligrams daily. If either component, when prescribed alone, fails to control your blood pressure, your doctor may try the Zestoretic combination, starting with either 10 or 20 milligrams of lisinopril and 12.5 milligrams of hydrochlorothiazide, and gradually increasing the dosage as needed.
If you are age 65 or older, or have kidney problems, your doctor will adjust your dosage with caution. This drug is not prescribed for people with severe kidney damage.
CHILDREN
Safety and effectiveness in children have not been established. |
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