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Primidone
Pronounced: pri-mi-done
Other Name(s): Mysoline
Primidone is used to treat epileptic and other seizures. It can be used alone or with other anticonvulsant drugs. It is chemically similar to barbiturates.
ADULTS
For people 8 years of age and older who have not been treated before, the recommended dosing of Primidone is as follows, using either 50-milligram or scored 250-milligram Primidone tablets:
Days 1 to 3: 100 to 125 milligrams at bedtime
Days 4 to 6: 100 to 125 milligrams 2 times a day
Days 7 to 9: 100 to 125 milligrams 3 times a day
Day 10 to maintenance: 250 milligrams 3 times a day
For most adults and children 8 years of age and over, the usual maintenance dosage is 250 milligrams 3 or 4 times a day. If you need more, your doctor may increase the dose to five or six 250-milligram tablets. You should not take more than 500 milligrams 4 times a day (2000 milligrams or 2 grams).
In patients already receiving other anticonvulsants, the usual starting dose of Primidone is 100 to 125 milligrams at bedtime; your doctor may gradually increase this dose to a maintenance level, as the other drug is gradually decreased. Your doctor may either find a working level for the combination or withdraw the other medication completely. When Primidone is to be used as a single drug, it may take at least 2 weeks to make the transition from two drugs to one.
CHILDREN UNDER AGE 8
Days 1 to 3: 50 milligrams at bedtime
Days 4 to 6: 50 milligrams 2 times a day
Days 7 to 9: 100 milligrams 2 times a day
Day 10 to maintenance: 125 milligrams 3 times a day to 250 milligrams 3 times day
The usual maintenance dosage is 125 to 250 milligrams 3 times daily or 10 to 25 milligrams per 2.2 pounds of body weight per day, divided into smaller doses. |
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