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Winnipeg, Manitoba
Canada R2W 3P2
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Amlodipine and Benazepril

Pronounced: (am-LOH-di-peen) & (ben-AY-ze-pril)
Other Names: None Listed
Catagory: Antihypertensive Combination
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Drug Information

This medicine is used to treat high blood pressure, either alone or with a diuretic (water pill).
Mechanism:
Amlodipine is called a calcium channel blocker. By blocking the flow of calcium across cell membranes, the contraction of heart muscle and the constriction of blood vessels is decreased, causing a lowering of blood pressure. The benazepril is called an ACE inhibitor, reducing blood pressure by preventing a chemical reaction that creates a potent vasoconstrictor. Use of the fixed combination is generally in those patients already stabilized on the separate medications individually.
More Info:
For more information about this medicine, talk to your healthcare provider.
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Side Effects

cough
Precautions:
It may be necessary to reduce the dose in patients with impaired kidney function.
Preganant:
There have not been well-controlled studies of Lotrel in pregnancy. Use only if clearly needed and the benefit outweighs any potential risk. Some ACE inhibitors have been shown to be excreted in breast milk in small quantities, so caution should be used in deciding whether to discontinue the drug or the breast-feeding.

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Dosage Information

This medicine is taken by mouth, usually once a day and may be taken with or without food.
Missed Dosage:
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
Storage:
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
Overdose:
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.

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