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Winnipeg, Manitoba
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Clozapine

Pronounced: (KLOE-za-peen)
Other Names: None Listed
Catagory: Antipsychotics
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Drug Information

Clozapine is a medicine that is used to treat schizophrenia. This medicine is usually prescribed when other antipsychotic medicines have not helped.
Mechanism:
Clozapine is part of a class of drugs called antipsychotics. This class of drugs works by decreasing abnormal excitement in the brain.
More Info:
For more information about this medicine, talk to your healthcare provider.
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Side Effects

Talk to your doctor if any of these side effects are bothersome or don’t go away: drowsiness, dry mouth, diarrhea, constipation, restlessness, headache
Precautions:
Clozapine can cause a serious blood condition that you need to be aware of. Your doctor will perform weekly blood tests for the first 6 months of treatment and once every other week after that.
Preganant:
There are no studies with this medicine in pregnant women. However, clozapine has not been shown to cause birth defects in animal studies. You and your doctor should decide whether the benefits of taking this medicine outweigh any risks to your baby. Clozapine may pass into breast milk. You should NOT breastfeed while taking this medicine. Talk to your doctor for more information.

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Dosage Information

Clozapine should be taken exactly as directed. It comes in tablet form and is taken orally one to three times a day. Your dose of clozapine may need to be adjusted, especially in the first few weeks. You will need to take weekly blood tests while taking clozapine and continue until 4 weeks after you stop taking clozapine. Initially, you will only receive a weeks supply at a time. Continue to take this medicine even if you are feeling better. This medicine must be taken for a few weeks for you to feel its full effects.
Missed Dosage:
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
Storage:
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
Overdose:
Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.

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